Biology

Using Competition Assays to Quantitatively Model Cooperative Binding by Transcription Factors and Other Ligands

*Background*: The affinities of DNA binding proteins for target sites can be used to model the regulation of gene expression. These proteins can bind to DNA cooperatively, strongly impacting their affinity and specificity. However, current methods …

Bioinformatic Description of tRNA Fragments and their Targets in Human AGO2

tRNA-fragments (tRFs) have recently been shown to play a regulatory role similar to miRNAs and have been linked to cancer, neurodegeneration and transgenerational epigenetic inheritance. tRFs are loaded into argonaute proteins (AGO) and incorporated …

Amino Acid-Dependent Stabiliy of the Acyl Linkage in aminoacyl-tRNA

Aminoacyl-tRNAs are the biologically active substrates for peptide bond formation in protein synthesis. The stability of the acyl linkage in each aminoacyl-tRNA, formed through an ester bond that connects the amino acid carboxyl group with the tRNA …

Obtaining Northwestern Atlantic salp Bloom Data Based on Newspaper Reports

Salp blooms are important and generally understudied components of the carbon cycle. Salp blooms of the northwestern Atlantic are particularly poorly studied. Using primary source non-science-oriented newspapers, we will attempt to supplement the …

𝘏𝘒π˜₯𝘳𝘰𝘴𝘒𝘢𝘳𝘢𝘴 𝘧𝘰𝘢𝘭𝘬π˜ͺπ˜ͺ Historic Trail

The *Hadrosaurus foulkii* Historic Trail tells the story of the revolutionary dinosaur discovery through nine relevant locations in Haddonfield, NJ. The trail visits the homes of prominent paleontologists Edward D. Cope and William P. Foulke, the …